Long-term IMPACT data find improved survival when targeted therapies matched to tumor-specific gene mutations

(University of Texas M. D. Anderson Cancer Center) Matching targeted therapies to tumor-specific gene mutations across tumor types improved progression-free survival (PFS) and overall survival (OS) in patients with advanced disease relative to those receiving non-matched treatment (NMT), according to research from The University of Texas MD Anderson Cancer Center. The researchers also found that receiving matched targeted therapy (MTT) was an independent factor for predicting longer OS.